Prof Ruparelia was awarded his medical degree from University College London in 2004 and an intercalated degree (BSc) in Medical Law receiving numerous prizes and subsequently completed specialist training in general cardiology and specialist coronary and structural through dedicated interventional fellowships in Oxford, London and Milan, Italy.

He was awarded a DPhil (PhD) from Balliol College, University of Oxford funded by a British Heart Foundation Clinical Research Fellowship and a MSc in interventional cardiology from the San Raffaele Scientific Instiitute in Milan, Italy. He was also the recipient of a British Heart Foundation travel fellowship to the Broad Institute (MIT) and Harvard Medical School (Boston, USA).

He is the winner of numerous prizes including President's Gold Medical in Cardiology from the Royal Society of Medicine and investigator prizes from the European Society of Cardiology (ESC), American Heart Association (AHA).

He is an author of >150 publications including original papers, editorials, review articles and book chapters and is regularly invited to speak at both national and International conferences and act as a reviewer for a number of international medical journals.

In 2017 he was awarded Fellowship of the European Society of Cardiology (FESC) and appointed Consultant Cardiologist between the Royal Berkshire Hospital, Reading and the Hammersmith Hospital, London.

In 2018, he was appointed Honorary Clinical Senior Lecturer at Imperial College London.

In 2020, he was appointed Visiting Professor at the University of Reading and awarded Fellowship of the Royal College of Physicians (FRCP).